About PDRN
PDRN is the heart of Lurena's skincare. Here we walk through the research, the origin and what we know.
PDRN. Origin and research.
PDRN, polydeoxyribonucleotide, is short DNA fragments. They're usually extracted from salmon or rainbow trout milt. The ingredient has been used in wound care and aesthetic medicine for decades. Today it's a talked-about name in K-beauty.
How PDRN works
PDRN activates a skin receptor called adenosine A2A. This kick-starts the body's own repair processes. Cells also get building blocks to form new DNA in damaged tissue. Research shows PDRN can support cell renewal, collagen production and blood vessel formation, as well as calm inflammation.
Injection or skincare – an important difference
Most research on PDRN concerns injections in wound care and aesthetic medicine, for example diabetic wounds and joint issues. The PDRN molecule is large, and large molecules don't easily pass through the skin. Topical skincare requires specially processed PDRN at a higher concentration for measurable effect. One study tested such a formula: an eye cream with 0.1 percent PDRN. After four weeks it gave better results than 0.1 percent retinol.
What this means for Lurena's products
Lurena's products contain PDRN at a low level, together with moisture and calming ingredients. PDRN is our signature ingredient and part of the story behind the brand. We don't promise clinical results and don't state figures for our own products. See the ingredient list on each product page for full information.
What is PDRN, really?
PDRN is short DNA fragments extracted from salmon or rainbow trout milt. The ingredient has been used in wound care for decades.
What has research shown PDRN can help with?
Studies show PDRN can support wound healing, collagen production and blood vessel formation in the skin. Most of the research concerns injections, not skincare products.
Is PDRN the same as in injection treatments at the dermatologist?
No. Injections deliver PDRN directly into the skin at a higher concentration. Skincare products, including ours, contain significantly smaller amounts.
Can PDRN in skincare give the same results as clinical studies?
We can't promise that. Research on topical PDRN is limited and requires specially processed formulas to work. Think of PDRN as part of our story, not a promise of results.
Is PDRN safe to use?
Studies describe PDRN as well tolerated with few reported side effects. Always consult a doctor if you have sensitive skin or are pregnant.